Prevalence of depression, anxiety and stress among school going adolescents in Delhi: a cross sectional study

Background: Adolescence is a stressful period due to physical, psychological, sexual changes and the presence of psychiatric disorders such as depression, anxiety and stress at this stage of life is a matter of concern. Depression is a common mental disorder, characterized by persistent sadness and a loss of interest in activities that you normally enjoy, accompanied by an inability to carry out daily activities, for at least two weeks. The objective of this study is to find the prevalence and associated factors of depression, anxiety and stress among school going adolescents.Methods: This was a school based descriptive cross-sectional study conducted in the month of July 2018 in an urban school in New Delhi. A semi-structured, self-administered questionnaire to assess socio-demographic profile as well as depression anxiety stress scale (DASS)–21 was used to assess depression, stress and anxiety.Results: Overall prevalence of depression, anxiety and stress were found to be 47.9%, 65.3%, and 51.8% respectively. Most of student suffered from moderate depression (46.8%), anxiety (33.3%) and mild stress (60.9%). It was noted that these were more common among female students, late adolescent age group, students alone/ away from family, students from separated/ single parents, consuming alcohol and family pressure to perform well in school.Conclusions: The alarming risk of depression, anxiety and stress among students with low academic satisfaction as well as those who face family pressure to perform better calls for need of parents-student counselling sessions, as well as frequent extracurricular activities to help create a healthier school environment.

Knowledge about obstetric danger signs among pregnant women attending antenatal clinic in a tertiary care hospital of Delhi: a cross sectional study

Background: According to UNICEF, globally 800 million women die due to preventable causes related to pregnancy and childbirth; 20% of which occur in India. It is therefore imperative to understand the level of knowledge about danger signs among pregnant women to augment timely redressal of preventive obstetric causes of mortality.Methods: A hospital based, cross sectional study was conducted at the ANC Clinic in Safdarjung Hospital, New Delhi from 2nd July to 27th July 2018. Convenient sampling was used to identify and interview 354 pregnant women, using a semi structured questionnaire. Data was entered and analysed with SPSSv21. Results were presented as frequencies and proportions. Chi square was used to test for association between qualitative variables, and p-value less than 0.05 was considered significant.Results: 48.3%, 35.6%, and 40.1% of pregnant women had knowledge about danger signs during pregnancy, labour and postpartum respectively. Majority of the women had knowledge about abdominal pain (58.4%) and severe fatigue (80.7%) as danger signs of pregnancy, while bleeding (82.5%) was the most common response as danger sign of labour. More than half had knowledge about heavy bleeding (59.9%) as danger sign of postpartum. The women lacked awareness about Convulsions (92.9%) as danger signs of pregnancy and labour, as well as smelly vaginal discharge (79.6%) in postpartum.Conclusions: Knowledge of obstetric danger signs among pregnant women is still lower. It needs further awareness as it can help in early diagnosis and referral of patients thus reducing maternal mortality and morbidity.

To Assess the Correlation between Bone Marrow Morphology and Immunophenotypic Findings in Patients of Chronic Lymphoproliferative Disorders (CLPD’s) and to Assess the Role of Flowcytometric Immunophenotyping in Diagnosis and Subclassification of CLPD’s

Introduction: Chronic lymphoproliferative disorderrepresent clonal proliferation of morphologically andimmunophenotypically mature B or T cells characterized by alow proliferation rate and prolonged cell survival. Study aimedto assess the correlation between bone marrow morphologyand immunophenotypic findings in patients of ChronicLymphoproliferative Disorders (CLPD’s) and to assess therole of flowcytometric immunophenotyping in diagnosis andsubclassification of CLPD’s.Material and Methods: 48 newly diagnosed cases ofCLPD were included. After complete clinical evaluation theyunderwent marrow aspiration, biopsy and immunophenotypingby flowcytometry with selected panel of monoclonalantibodies.Results: On morphology 47.9% cases were CLL. In 52.1%non CLL cases , 4.2% were PLL , 2% case as LPL and45.8% cases were CLPD-unclassifiable. Commonest patternof marrow infiltration noted on trephine biopsy was diffuse inCLL, HCL-V, B-PLL and T-CLPD. On immunophenotyping95.8% cases were B-CLPD and 4.25% T-CLPD. CD5, CD22,CD23, FMC7 and SmIg were used as first line markersfollowed by CD 10, CD 25, CD103, CD38, CD138 andCyclin D1 (on biopsy sections) as second line markers. Finalimmunophenotypic diagnosis was CLL (54.2%), B-CLPDunclassified (29.2%), 4.1% each of LPL, MCL, T-CLPD and2% each of B-PLLand HCL-V.Conclusion: Concordance rate between morphologicaldiagnosis and immunophenotypic diagnosis was 79.17%.Hence, Flowcytometry is necessary for confirmationof diagnosis and to classify the CLPD cases which areunclassifiable by morphology

Breastfeeding and an overweight child: A linkage.

Assunção ML, Ferreira HS, Coutinho SB, Santos LM, Horta BL. (Postgraduate Programme in Nutrition, Faculty of Nutrition, Federal University of Alagoas, Maceió, Alagoas; Postgraduate Programme in Child and Adolescent Health, Federal University of Pernambuco, Recife, Pernambuco; Department of Public Health, University of Brasília, Brasília, Federal District; Postgraduate Programme in Epidemiology, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.) Protective effect of breastfeeding against overweight can be detected as early as the second year of life: A study of children from one of the most sociallydeprived areas of Brazil. J Health Popul Nutr 2015;33:85–91.

Predication of Parkinson's disease using data mining methods: A comparative analysis of tree, statistical, and support vector machine classifiers.

The prediction of Parkinson's disease in early age has been challenging task among researchers, because the symptoms of disease came into existence in middle and late middle age. There are lots of symptoms that lead to Parkinson's disease. But this article focuses on the speech articulation difficulty symptoms of PD affected people and try to formulate the model on the behalf of three data mining methods. These three data mining methods are taken from three different domains of data mining i.e., from tree classifier, statistical classifier, and support vector machine classifier. Performance of these three classifiers is measured with three performance matrices i.e., accuracy, sensitivity, and specificity. Hence, the main task of this article is tried to find out which model identified the PD affected people more accurately.

Prevalence, awareness, treatment and control of hypertension among the elderly in a resettlement colony of Delhi.

BACKGROUND: With the increase of the elderly population in India, chronic diseases like hypertension are becoming an important public health problem. Thus, the present study was carried out to assess prevalence, awareness, treatment, and control of hypertension among elderly in a resettlement colony of Delhi. METHODS: A community-based cross-sectional survey was carried out, using systematic random sampling technique. A total of 294 (119 male and 175 female) subjects aged 60 years or more were studied. Of the total subjects, 210 (71%) were in 60-69 years, 57 (19.47%) were in 70-79 years, and 27 (9.2%) were more than 80 years of age. Blood pressure of each subject was measured on two visits, 1 week apart and was graded according to World Health Organization-International Society of Hypertension/VI Joint National Committee on Prevention, Detection, Evaluation, and Treatment of high blood pressure guidelines. Anthropometric variables and other associated risk factors were also studied. RESULTS: Hypertension was present in 116 subjects (39.5%), it was more among males 49 (41%) as compared to females 67 (38%). Among the hypertensive subjects, 60 (51.7%) were aware of their condition, 45 (39%) were on treatment, and 17 (14.67%) were controlled on treatment. Level of awareness and treatment were significantly higher among the females. Body mass index of 25 or more and alcohol consumption were found to be significantly associated with risk of having high blood pressure. CONCLUSION: Prevalence of hypertension in the present study was 39.5%, while level of awareness, treatment, and control were 50%, 39%, and 14.6%, respectively.